Labels:text | screenshot | black and white | black | document OCR: adrenal Hydroxylation steps in the biosynthesis ular steroids (Fig. 7.7) require NADPH, mole nplex oxygen, and an enzyme complex. The co a. odoxin), consists of a flavoprotein dehydrogenase nonhaem iron-containing protein (adre aracteristic and cytochrome P450 (so called since a ch plexes withhigh absorption is observed when it com carbon monoxide). This oxidase system i id essentially similar for 11ct -, 20,22 -, 17ct- a ificity is 18-hydroxylation, and it appears that spe ective P450 achieved through differences in the resp by the cytochromes. Hydroxylation is mediated tron introduction of one electron into the ele one atom transport chain, with the introduction o rater. This atom combines with hydrogen to form v g oxygen of oxygen into the steroid. The remainir idase'. system is known a ...
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